Overview of Picked Chemical Compounds and Intermediates
Overview of Picked Chemical Compounds and Intermediates
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1. Pharmaceutical Intermediates
Bortezomib Acid Impurity: That is an impurity associated with bortezomib, a proteasome inhibitor Utilized in the treatment method of numerous myeloma. Its synthesis or study is crucial for making sure the purity and basic safety on the drug.
Abiraterone Acetate Intermediate (CAS NO. 122111-01-7): A precursor inside the synthesis of abiraterone acetate, a drug Employed in the treatment method of prostate cancer by inhibiting androgen manufacturing.
Imatinib Intermediate (CAS NO. 152460-ten-1): A essential compound from the synthesis of imatinib, a drug that targets specific different types of cancer, including Long-term myelogenous leukemia (CML).
Docetaxel Intermediate: A compound used in the synthesis of docetaxel, a chemotherapy medication that treats several cancers like breast, lung, and prostate most cancers.
2. Chemical Impurities and Byproducts
GeMcitabine Intermediates (T6, T9, 8): These are intermediates while in the synthesis of gemcitabine, an anti-most cancers drug. Their research is important for optimizing the creation procedure and ensuring substantial purity.
Lapatinib Intermediate (CAS NO. 231278-eighty four-5): Lapatinib is utilized to take care of breast most cancers, and these intermediates are associated with its output.
Fulvestrant Intermediates: Fulvestrant is definitely an estrogen receptor antagonist Utilized in the procedure of breast cancer. Various intermediates assist in the synthesis of the drug.
Paclitaxel Facet Chain Acid (CAS NO. 949023-sixteen-9): This intermediate is used in the synthesis of paclitaxel, a chemotherapy drug productive in managing cancers like ovarian, breast, and lung cancer.
3. vildagliptin intermediates Other Notable Compounds
Irinotecan Hydrochloride Trihydrate (CAS NO. 136572-09-three): A chemotherapy drug Employed in the therapy of colorectal cancer and modest mobile lung most cancers.
three-Amino-1-hydroxyadamantane (CAS 702-eighty two-9): This compound is involved with the synthesis of adamantane derivatives, that have a variety of programs, like antiviral Attributes.
Vildagliptin Intermediates: Used in the creation of vildagliptin, an oral drug for sort two diabetic issues that inhibits the enzyme DPP-4 3 to control blood sugar amounts.
four. Miscellaneous Compounds
D-Gluconic Acid δ-Lactone (CAS NO. 61259-forty eight-one): This compound is involved with the synthesis of varied gluconic acid derivatives, that happen to be Utilized in food items, pharmaceutical, and industrial apps.
Canagliflozin Intermediate 2: A precursor inside the synthesis of canagliflozin, a medication employed to deal with sort 2 diabetes by inhibiting sodium-glucose co-transporter 2 (SGLT2).